Genome and Stem Cell Plasticity in Development and Ageing
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Responsable:![]() Jean-Marc
LEMAITRE Coordonnées
email: jean-marc.lemaitre[a]inserm.fr Group
LEMAITRE Jean-Marc (DR/Inserm) Keywords
aging epigenetics senescence chromatin replicative stress rejuvenation regeneration pluripotency iPSC reprogramming disease modeling Technical skills
Culture cell : Cell lines, primary fibroblates and keratinocytes, Neural stem cells (NSC), Hematopoietic stem cell (HSC), Mesenchymal stem cells (MSC), pluripotent stem cells (ESC and iPSC)
Gene expression : Transcriptomics, RNA seq Epigenetics: CHiP seq, HI-C Replication studies: Replication timing analysis genome-wide, Origin mapping SNS purification. Bioinformatics Reprogramming strategies iPSC Diffrentiation protocols into fibroblates, keratinocytes, NSC, HSC, MSC, cardiomyocytes Mice models |